BCAAs are shown to have anabolic effects in human muscle. They are required
for muscle tissue maintenance and preserve glycogen stores in muscle tissue. The
BCAAs are the primary amino acids responsible for protein synthesis. In fact,
the tissue building effects from protein are primarily due to BCAAs.
The anabolic activity of BCAAs are from multiple pathways. Studies show that the
BCAAs and in particular leucine stimulates muscle protein synthesis by acting as
both a signal and a substrate. One way BCAAs do this is through signaling mTOR
activity in human muscle tissue. mTOR is the primary regulator of muscle growth
through amino acid sensoring. BCAAs appear to signal mTOR to activate protein
synthesis after exercise.
This is a significant anabolic signaling effect activated by BCAA.
Anti-Catabolic Effects of BCAA
BCAAs effect on increasing lean muscle tissue stems from its anabolic activity
as well as its anti-catabolic activity. Studies show taking BCAAs before
training is effective at suppressing muscle tissue breakdown after training.
These study results suggest that BCAAs have a protein-sparing effect during the
recovery after exercise, and that protein synthesis is stimulated and/or protein
degradation is decreased. There are also indications, though difficult to
measure, that these same effects happen during exercise as well.
With BCAA supplementation you get greater protein synthesis and less protein
breakdown.
Reduce Muscle Damage and Soreness
BCAAs reduce training induced muscle damage and soreness. Studies performed on
athletes supplementing with BCAA showed reduced levels of key markers indicative
of muscle damage, reduced inflammation, and effectively reduced perceived muscle
soreness.
Blood samples after BCAA intake showed dramatic decreases in creatine kinase
(CK) and lactate dehydrogenase (LDH) – both markers of muscle damage. Lower
levels of CK and LDH indicate less muscle tissue damage and inflammation. Less
muscle damage, soreness and inflammation leads to quicker recovery times. Your
body spends more time in anabolic mode.
BCAAs Reduces Fatigue and Enhance Endurance
One unique effect of BCAA is its prevention of central fatigue allowing for high
intensity training for longer periods of time. Research on BCAA supplementation
during exercise does show they increase mental alertness and reduce mental
fatigue.
In the blood stream BCAAs compete with tryptophan (the tranquilizing amino
acid). Tryptophan is the direct precursor to the neuro- transmitter serotonin.
This depresses the central nervous system and produces symptoms of fatigue. When
you exercise intensely, the ratio of tryptophan to BCAA is altered in favor of
increases in tryptophan. This in itself makes you fatigued. Several studies with
various types of athletes confirm that BCAAs reduce mental fatigue and increase
mental alertness during their respective events.
Less fatigue during exercise and other physical activities as well as sharper
mental focus and concentration supports enhanced athletic performance. Anytime
you can train harder and concentrate better you’ll get results faster.
Fast Ball Stays Fast
An interesting sport specific study (baseball) showed BCAA supplementation
prevented the drop in pitching velocity that occurs after approximately 100
pitches – delaying fatigue and extending muscular endurance. In this rather
unique study, college and pro level pitchers supplementing with BCAA showed no
abrupt drop in pitching speed when those that didn’t supplement saw significant
speed decreases. BCAAs could spell the end to the “Closer” in Major League
Baseball.
While studies show significant decreases in training fatigue other studies also
show BCAA supplementation enhances endurance by extending time to exhaustion
during exercise.
Get Anabolic - Stay Anabolic!
As you can see, BCAAs are the most extensively researched amino acids. When it
comes to turning on anabolic activity in muscle tissue while turning off
anti-catabolic activity, no other amino acids have show shown such direct
effect.
To sum up what BCAA 4500 can do for you – increase anabolic effects of exercise,
decrease anti-catabolic effects of exercise, reduced muscle damage, reduce
muscle soreness during and after exercise, decrease recovery time, increase
mental focus, decrease mental and physical fatigue, increase endurance, and
enhance protein synthesis.
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